What is THF? What's the role?

THF is an important organic synthetic raw material and a solvent with excellent performance. It is applied to resin solvent (tape coating, PVC surface coating, cleaning of PVC reactor, removal of PVC film, cellophane coating, plastic printing ink, thermoplastic polyurethane coating); Reaction solvent (Grignard reagent, alkyl alkali metal compound and aryl alkali metal compound, aluminum hydride and boron hydride, steroid compound and macromolecular organic polymer); Chemical intermediate products (polymerization to produce PTMEG and natural gas flavoring agent); Chromatographic solvent (gel permeation chromatography). Used as solvent and raw material for organic synthesis.

THF itself can be condensed into polytetramethylene ether glycol (PTMEG), also known as tetrahydrofuran homopolyether. PTMEG and toluene diisocyanate (TDI) are made of special rubber with wear resistance, oil resistance, good low-temperature performance and high strength; With dimethyl terephthalate and 1,4-butanediol, block polyether polyester elastic material is prepared.

In organic synthesis, it is used to produce tetrahydrothiophene, 1.2-dichloroethane, 2.3-dichlorotetrahydrofuran, pentolactone, butyrolactone and pyrrolidone.

In the pharmaceutical industry, THF is used to synthesize Kebiqing, Rifamycin, progesterone, etc. THF is treated with hydrogen sulfide to produce tetrahydrothiophenol, which can be used as odorant (identification additive) in fuel gas. THF can also be used as a surface treatment agent for synthetic leather.